1. Turn off the Vista security feature that is crashing Killer systray when it attempts to make the download:
Control Panel > User Accounts > User Account Control > OFF, and you are prompted to reboot. Reboot, and systray will prompt you to download the new drivers without crashing.
OR
2. Ignore the systray prompt (let it crash), then manually launch the Killer Config from your system tray. Follow the update prompts from this point. Because the 'user' opened the program, it now will be able to download the update properly.
OR
3. Go to https://www.killernic.com/support and manually download the latest Killer Drivers for your operating system, and install them manually.