I've tried everything I can think of.  I've tried the MB outside the case, on a wood desk, (That was a lot of work!)  I changed out the 2133 mhz Patriot memory and bought some Corsair 1600 mhz memory.  I've tried all the settings on Auto, and I've tried putting in the memory spec's manually.  I've reseated the video cards and tried running with one card, then the other, then both again.  I've reseated the CPU and applied new thermal paste to my CPU before reinstalling my Antec Kuhler 920.  Nothing gets the USB 3.0 ports to start working correctly.  All they will do is occasionally read a flash drive, nothing else.
 
I've flashed the #37 BIOS to all three positions on the switch, and tried all three of them with the new memory and various settings.
 
Today, even with everything set at stock speeds and doing nothing more than surfing the 'net and doing some work with MS Word and Excel, I got two BSOD's, one blank, pure red screen, (Never seen that one before!), and the computer froze up several times.  Then I started getting the error message that a USB port had overvolted.  That wouldn't go away until after two reboots.
 
All the temps seem normal, and I wasn't doing anything especially taxing on the computer except word processing or my wife looking at things on the internet.
 
Should I give up and ask for an RMA on this MB?